Which character makes a decision that results in destruction and pain A Tale of Two Cities by Charles Dickens

One of the most infamous of characters in all of classical
literature, Therese Defarge is the quintessential villain in A Tale of Two
Cities by Charles Dickens.  As the surviving sister of the family that has 
long been brutalized by the twins Evremonde, Madame Defarge vows vengeance upon them and
theirs.  Into her cloth of death, Mme. Defarge records the names of the Marquis
d'Evremonde, Charles Darnay, ne Evremonde, Gabelle his tax collector, Lucie Manette
Darnay, wife of Charles, and their children, and her father, Alexandre Manette--the
entire family.  When her husband, Ernest Defarge suggests that some mercy could be shown
to Manette, she cruelly and coldly retorts,

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"Then tell Wind and Fire where to stop...but
don't tell me."

Defarge, a weak minority, interposed a few
words for the memory of the compassionate wife of the Marquis; but, only elicited from
his own wife a repetition of her last reply, "Tell the Wind and the Fire where to stop;
not me!"

Even as she waits
for the execution of Charles Darnay (not knowing that Carton has taken his place), the
vengeful Mme. Defarge leaves her seat to seek Lucie and her children and personally kill
them so that no one of the family remain.

Of course, Madame
Defarge's personal vendetta is also responsible for some of the events of the French
Revolution as she uses this revolt as the vehicle for her personal acts of revenge. 
And, in her hatred for the Evremonde, she extends this enmity to all aristocrats and
knits their names, too, into her cloth of death.